On the other hand, good men can be false-positive results and overtreatment, adding an element of risk, the researchers report widescale screening to 31. March online issue of the BMJ.
"According to our findings, I would say that the benefit of the classification is not sufficient to support the mass screening," said study author Dr. Gabriel Sandblom, associate professor at Karolinska Institutet in Stockholm.
"However," he added, "the study of Sandblom was initiated more than 20 years ago, when the DOG [prostate specific antigen testing] were not available and the treatment of localized prostate cancer has not been as effective as it is today. Therefore, I recommend the PSA testing nor categorically on the basis of individual decisions from a man who feels concerned about prostate cancer. "
This Council is not in accordance with the recently updated guidelines for screening for prostate cancer from the Government of the United States of America. The recommendations, released in 2008, critically prostate cancer screenings in any age, healthy men and definitely recommend against them exclusively for men over 75.
American society for cancer also recently revisited the question of screening for prostate cancer.
"A little over a year ago, the American society for cancer to revise its guidelines, which reinforces the message that men need to be informed, that are known advantages, but also the boundaries of the projection, the DOG," said Dr. Durado Brooks, Director of prostate cancer and Colon cancer in American society. "The American Cancer Society, and is not to encourage or discourage them from prostate cancer screenings.
This new study to carry with him a number of important weaknesses, said Brooks. In particular, due to the timing and design studies, most men only received one and at most two PSA tests.
"At best, it is the study of one or two tests of the DOG in men in their late 50 's and early 1960 's," he said.
For the study, researchers looked at all the people in the Swedish city of Norrkoping, who were aged 50 to 69 in 1987, a total of 9,026 people.
One of them was 1,494 men detection prostate cancer – first with the digital sound (DRE) and since 1993, DRE and PSA tests – every three years.
In 1996, were reviewed, only men aged 69 or below.
The remaining men have undergone screening and 7532 served as the Group of comparison.
Mortality rate of men who have been subjected to examination was not significantly different in the control group, although the tumors in the screened group rather smaller and more localized.
Commenting on the study, Dr. Chad LaGrange, Professor of Urology at the University of Nebraska Medical Center in Omaha, said he believes that the findings add "much greater uncertainty" already complex issue.
More and more research on this topic, "the guidelines have become vague recommendations," he said. "We have no really no rules."
The bottom line: "it's not just as simple as a DOG or a screening work. Patients should talk with their doctor about it, "said LaGrange. "PSA testing should not be just a reflex."
But the good news is hidden here is that the number of deaths from prostate cancer continues to decline, whether it be a better classification or better treatment, he said. "We're doing something right," said LaGrange.
SOURCE: Gabriel Sandblom, M.D., Ph.d., Associate Professor, Karolinska Institute, Stockholm, Sweden; Chad LaGrange, m.d., Assistant Professor, urology, University of Nebraska Medical Center, Omaha; Durado Brooks, m.d., Director, prostate cancer, and colon, American society for cancer, Atlanta; March 31, 2011, BMJ, online
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